I was at the CP+ convention last month when Fuji unveiled the X-Pro1 and played with the camera a bit. I have to say that I was very disappointed in its lens work. Basically I found both the auto-focus useless as it hunted far too much, even in a well-lit environment. I was never sure of whether the focus was achieved unless I was in EVF mode, which seemed to defeat the purpose of an optical viewfinder.
In manual focus, the stock Fuji lenses seemed to be very "detached" from the focus ring. I didn't have the confidence that I could snap focus like I could with a Leica M rangefinder.
The worst aspect though of manual focusing was that there was only one manual focusing aid -- the magnified view option. This is good but is now a bit dated.
I decided instead to get a Ricoh GXR base camera and plan to get an M-module very soon. I've already tested this setup and I found that the contrast-highlight manual focus option on the GXR is very fast and accurate -- as accurate as my rangefinding focus. Will report on this setup more as I get more experience with it.